BackgroundJuvenile idiopathic arthritis (JIA) is a serious and potentially debilitating pediatric illness.Improved disease self-management may help to improve health outcomes.ObjectiveThis study aimed to evaluate the effectiveness of the Teens Taking Charge Web-based self-management intervention in reducing symptoms and improving health-related qua
Disease-associated mutations prevent GPR56-collagen III interaction.
GPR56 is a member of the adhesion G protein-coupled receptor (GPCR) family.Mutations in GPR56 cause a devastating human brain malformation called bilateral frontoparietal polymicrogyria (BFPP).Using the N-terminal fragment of GPR56 (GPR56(N)) as a probe, we have recently demonstrated that collagen III is the ligand of GPR56 in the Cleaning Supplies
Restless Legs Syndrome: Known Knowns and Known Unknowns
Although restless legs syndrome (RLS) is a common Faber High Light Ceiling hood 91cm Matt White Perimeter LED Lights 110.0456.206 neurological disorder, it remains poorly understood from both clinical and pathophysiological perspectives.RLS is classified among sleep-related movement disorders, namely, conditions characterized by simple, often stere
An improved strategy for generating forces in steered molecular dynamics: the mechanical unfolding of titin, e2lip3 and ubiquitin.
One of the applications of Molecular Dynamics (MD) simulations Faber High Light Ceiling hood 91cm Matt White Perimeter LED Lights 110.0456.206 is to explore the energetic barriers to mechanical unfolding of proteins such as occurs in response to the mechanical pulling of single molecules in Atomic Force Microscopy (AFM) experiments.Although Steered
Economic offenses from application to the verdict in the Republic of Serbia
The main research problem is the correlation between applications, indictments and verdict for economic offenses in the Republic of Serbia.The subject of this paper is the analysis of the correlation of economic offenses in the chain of criminal justice system from the application to the verdict Air Compressor as a whole, but also separately, from